Inhibitory control of hippocampal inhibitory neurons
نویسندگان
چکیده
منابع مشابه
Inhibitory control of hippocampal inhibitory neurons
Information processing within neuronal networks is determined by a dynamic partnership between principal neurons and local circuit inhibitory interneurons. The population of GABAergic interneurons is extremely heterogeneous and comprises, in many brain regions, cells with divergent morphological and physiological properties, distinct molecular expression profiles, and highly specialized functio...
متن کاملSynapse-Specific Inhibitory Control of Hippocampal Feedback Inhibitory Circuit
Local circuit and long-range GABAergic projections provide powerful inhibitory control over the operation of hippocampal inhibitory circuits, yet little is known about the input- and target-specific organization of interacting inhibitory networks in relation to their specific functions. Using a combination of two-photon laser scanning photostimulation and whole-cell patch clamp recordings in mi...
متن کاملInhibitory control of intrinsic hippocampal oscillations?
An oscillatory mode of activity is a basic operational mode of the hippocampus. Such activity involves the concurrent expression of several rhythmic processes, of which theta (4-15 Hz) and gamma (20-80 Hz) oscillations are prominent and considered to be important for cognitive processing. In an experimental model that preserves the intrinsic network oscillator, exhibiting the dependency on chol...
متن کاملGabapentin increases a tonic inhibitory conductance in hippocampal pyramidal neurons.
BACKGROUND The mechanisms underlying the therapeutic actions of gabapentin remain poorly understood. The chemical structure and behavioral properties of gabapentin strongly suggest actions on inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA); however, gabapentin does not directly modulate GABAA or GABAB receptors. Two distinct forms of GABAergic inhibition occur in the bra...
متن کاملPrefrontal – hippocampal pathways underlying inhibitory control over 5 memory
29 A key function of the prefrontal cortex is to support inhibitory control over behavior. It is widely believed 30 that this function extends to stopping cognitive processes as well. Consistent with this, mounting evi31 dence establishes the role of the right lateral prefrontal cortex in a clear case of cognitive control: retrie32 val suppression. Retrieval suppression refers to the ability to...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2012
ISSN: 1662-453X
DOI: 10.3389/fnins.2012.00165